Imiti myinshi kandi myinshi irimo ibikoresho bya farumasi bikora neza (API), bisaba gufata neza no gukoresha ibikoresho kabuhariwe. Hano, Precision Polymer Engineering (PPE) yibanda kumpamvu ibice byikinyugunyugu bigabanijwe bitanga ibisubizo bidahenze hamwe no gusobanukirwa byimbitse ibikoresho byiza byo gufunga inzira yo gufunga.
Igice kinini cyimiti mishya irimo gutunganywa kirimo imiti ikora neza cyane (APIs), biganisha ku kwiyongera guturika gukenera umusaruro.
Nyamara, cytotoxicity ya APIs itanga imbogamizi nyinshi, zirimo gutunganya ibiyigize no gukenera gushora imari muri kontineri yihariye kugirango abakozi n’ibikorwa byabo bitagaragara.
Ni izihe mbaraga zitwara inzira nziza yo gukumira, kandi ni izihe mbogamizi zugarije ababikora?
Ubwiyongere bw’ibintu bikora cyane n’amabwiriza akomeye ku bijyanye n’imikorere y’ibidukikije n’ibidukikije byatumye ubwiyongere bukabije ku isi bukenera ibikoresho bifunga kashe.
Ibiyobyabwenge bigenda byiyongera bisaba inganda guhindura byinshi muburyo bwo gutunganya ibihingwa nuburyo bukoreshwa kugirango habeho kubihaza bihagije. Ariko, ibyateganijwe kurubu kurwego rwibintu akenshi birenze kure ubushobozi bwibikoresho byateguwe kandi bikozwe mu myaka mike ishize.
Mugihe uhitamo ibimenyetso bifunga ibikoresho byinshi, umuntu agomba gutekereza kubibazo bishobora kuvuka mugihe habaye kumeneka cyangwa kashe ya valve:
Ibikoresho bikora neza nka hormone, retinoide, antibiotique zimwe na zimwe hamwe na anesthetike bisaba kugenzura bidasanzwe mugihe cyo gutunganya. Ibi bisobanurwa nakazi ntarengwa (OEL) cyangwa itsinda ryabakozi (OEB) ryahawe ibiyobyabwenge bikora.
Amateka, ibikoresho byo kurinda umuntu byakoreshejwe mukurinda ingaruka. Nubwo, ari ngombwa nta gushidikanya ko kurinda abakozi, hari ibyago byo kwanduzanya mu kazi bitewe no kohereza ibicuruzwa bivuye mu myenda ikingira ndetse n’akazi keza.
Mu rwego rwo kurinda abakoresha ibikoresho no kugabanya urwego rwanduza ibicuruzwa kuva kuri microgramu kugeza kuri nanogramu, birakenewe ko uruganda rwa farumasi ruteza imbere ingamba zarwo.
Ariko, ibibazo birashobora kuvuka mugihe ugerageza gushaka ibisubizo byibikoresho nibikoresho bihari. Hashingiwe kuri iki gitekerezo, PPE yizera ko kongera SBV bishobora kwerekana ko ari igisubizo cyigiciro, cyane cyane iyo umwanya hamwe nimbogamizi zibikoresho bigabanya amahitamo ahari. Iyi mibande yerekanye ko ishobora kuzuza intego zateganijwe zisabwa kugirango ikemure API.
Mugihe cyo guhererekanya ifu yingirakamaro kuva murwego rumwe ikajya kurindi, SBV igabanya ingano yibice byangiza ikirere. Ikintu cyibanze kiranga SBVs zose nuko zigizwe nibice bibiri bihujwe hamwe, aribyo bikora "Alpha" bikora hamwe na pasitoro "Beta".
Buri gice kigizwe na kimwe cya kabiri cya "ikinyugunyugu", kandi disiki yikinyugunyugu ifunzwe kumubiri nyamukuru hamwe na kashe ya elastike kugirango ikore ikigo gifunze cyane. Ikidodo cya Elastomerique gikoreshwa nk "intebe" muri buri gice, kandi kimaze guhuzwa hamwe, bitanga kashe nziza hagati yimikorere ikora neza.
Indangantego hamwe nibice bya elastomer bikunze guhura nimiti itandukanye hamwe nu mashanyarazi, nkibikoresho byangiza. Kubwibyo, imiti ihuza ibikoresho bya elastomer muburyo ubwo aribwo bwose bwo gufunga ni ikintu cyingenzi cyo gusuzuma.
Abakora ibicuruzwa bya Valve bamaze igihe kinini bashingira kubikoresho nka EPDM (Ethylene propylene terpolymer) nkibikoresho byatoranijwe ku miti ya SBV yimiti. Ariko, uko imikorere ya API yiyongera, harasabwa ibikoresho byinshi bya elastomer.
PPE irasaba gukoresha intebe ya perfluoroelastomer (FFKM) ya valve muburyo bukoreshwa muburyo bwa chimique. Ibikoresho byiza bya FFKM, byahujwe no kurwanya imiti hafi ya yose (bisa na PTFE) hamwe nubushuhe buhebuje (kuva -30 ° C kugeza kuri +325 ° C), bituma biba byiza kuri SBVs zikoreshwa muburyo bunoze bwo gutunganya API guhitamo.
Binyuze mu bikoresho byoroheje no gutekereza kubintu, nko gukoresha icyicaro cya FFKM aho gukoresha icyicaro cya EPDM muri SBV, birashoboka kwagura ubushobozi bwimikorere ya valve ndende ya hermetic idafite ibiciro bishya.
Igihe cyo kohereza: Nyakanga-08-2021
